TRON-Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz gGmbH ist ein biopharmazeutisches Forschungsinstitut, das neue Diagnostika und Arzneimittel für die Therapie von Krebs und anderen Erkrankungen mit hohem medizinischem Bedarf entwickelt. Der Schwerpunkt von TRON liegt in der Entwicklung neuer Plattformen für personalisierte Therapiekonzepte und Biomarker, und somit in der Überführung grundlagenorientierter Forschung in die Entwicklung neuer Arzneimittel. In Zusammenarbeit mit akademischen Institutionen, Biotechnologiefirmen und der pharmazeutischen Industrie kommen in der Forschung am TRON modernste Technologien zum Einsatz. Zudem stellt TRON seine einzigartige Expertise und Infrastruktur der Entwicklung von innovativen Arzneimitteln zur besseren Patientenversorgung zur Verfügung.

Spotlight

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TRON Teams wins Silv…
Silber für TRON bei der diesjährigen Mainzer Benefizveranstaltung “Rudern gegen Krebs”!
Posted 3 Monaten ago

Mainz, 01. September - Auch in diesem Jahr fand am 28.08.2016 die jährliche Benefizveranstaltung „Rudern gegen Krebs“ auf dem Rhein vor der Malakoff-Terrasse statt. Die Veranstaltung, die dieses Jahr hochwasserbedingt vom Juni in den August verlegt werden musste, war mit 85 gemeldeten Teams wieder gut besucht.

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TRON/BioNTech Nature…
TRON article featured in renowned Nature Journal
Posted 6 Monaten ago

Mainz, June 01, 2016
An interdisciplinary collaboration led by TRON Managing Director Prof. Dr. Ugur Sahin establishes RNA-Lipoplexes as universally applicable novel vaccine class for iv DC targeting utilizing both adaptive as well as innate immune mechanisms for cancer immunotherapy:
“Systemic RNA delivery to dendritic cells exploits antiviral defense for cancer immunotherapy”.

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TRON at CIMT2016
TRON at CIMT2016
Posted 7 Monaten ago

Mainz, 10 - 12 May 2016 – TRON at CIMT 2016
“Mechanisms of Efficacy in Cancer Immunotherapy”
Looking forward to the 2016 Annual Meeting of Cancer Immunotherapy in Mainz. Connect with us at booth A021 or at any of our posters.

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Review by TRON/BioNT…
TRON Review in Clinical Cancer Research
Posted 8 Monaten ago

Mainz, April 2016 – Review in CCR Focus "Opportunities and Challenges in Cancer Immunotherapy":
“Targeting the Heterogeneity of Cancer with Individualized Neoepitope Vaccines”
TRON and BioNTech scientists have written an overview of the clinical development of individualized neoepitope cancer vaccines, which is published now as CCR Focus Review article in Clinical Cancer Research.

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Prof. Peer from the …
TRON / BioNTech in Nature Medicine News
Posted 10 Monaten ago

Mainz, February 2016
TRON/BioNTech in Nature Medicine News Feature:
“Mutations as munitions: Neoantigen vaccines get a closer look as cancer treatment”
TRONs efforts to develop individualized cancer vaccines based on tumor-specific mutations is covered in a recent News Feature published in Nature Medicine.
For more information please click the Link below, which will direct you to the Nature Medicine website featuring the article.

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Prof. Peer from the …
Prof. Peer from the Tel Aviv University (TAU), Israel, visiting TRON
Posted 1 Jahr ago

Mainz, October 2015 – TRON Seminar in Translational Oncology
“RNA Therapeutics : New Era in Personalized Medicine?” 
Prof. Dan Peer, PhD - Department of Cell Research and Immunology, Tel Aviv University (TAU), Israel
5 PM, Lecture Hall Building 708, University Medical Center Mainz
Langenbeckstr. 1, 55131 Mainz, Germany

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Prof. Schoenberger f…
Prof. Schoenberger from the La Jolla Institute for Allergy and Immunology visiting TRON
Posted 1 Jahr ago

Mainz, July 2015 – TRON has the honor to host visiting Prof. Stephen Schoenberger at its facilities to promote international scientific interactions and facilitate collaborations in the fields of Immunology and Immunotherapy. Prof Schoenberger is co-author on a recent publication in Nature by TRON scientists focusing on mutated epitopes in cancer.  During his time at TRON Prof. Schoenberger will interact with different scientific teams and delve deeper into the various scientific challenges of individualized cancer vaccine research.

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Besuch einer Delegat…
Besuch einer Delegation aus dem Sultanat Oman im TRON
Posted 1 Jahr ago

Mainz, June 2015 – On June 1st and with generous support of the Ministry of Economics of Rhineland Palatinate, TRON welcomed a high-ranking delegation from the Sultanate of Oman for discussions on tasks and results of previous scientific works at TRON. Prof. Dr. Ulrich Förstermann of the Mainz University Medical Center also took part in the discussions.

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TRON is part of the …
TRON is part of the Cancer Research Consortium “Immuno-Transporter” to collaborate to develop innovative appro…
Posted 1 Jahr ago

Mainz, June, 2015 – The consortium partners will jointly develop methods to achieve tumor-specific activation of a patient's immune system to make it recognize, target and fight cancer
The newly established "IMMUNO-TRANSPORTER" consortium will collaborate to develop innovative approaches in the field of cancer immunotherapy. 

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TRON is part of the …
TRON is part of the European Bioinformatics Research Consortium on personalised cancer immunotherapy
Posted 2 Jahren ago

Mainz, May 1, 2015 – Experts in bioinformatics and cancer immunology to develop an Advanced bioinformatics platform for personalised cancer immunotherapyOn May 1st, TRON under the leadership of Prof. Dr. med. Ugur Sahin started an innovative research project on personalised cancer immunotherapy.

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News

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11 Fakten über Krebs
Posted 1 Woche ago

Mainz, 23. November 2016 – Wie entstehen Krebszellen? Ist Krebs erblich? Warum ist es so schwer, Krebs zu behandeln/zu heilen und welche neuen Ansätze zur Krebsbehandlung gibt es? Welche Rolle spielt dabei die individualisierte Immuntherapie – und was ist das überhaupt? TRON und BioNTech tragen 11 Fakten über Krebs zu "Wissen im Herzen" bei, eine Video-Serie der…

SITO – Seminars in T…
Posted 4 Wochen ago

Mainz, November 17 'The immune biology of microsatellite instability cancer: Towards a vaccine against HNPCC', Prof. von Knebel Doeberitz from the Institute of Pathology at the University of Heidelberg will speak in our seminar on Thursday during his visit at TRON.

SITO – Seminar…
Posted 1 Monat ago

Mainz, November 10 'Inducing Neoantigens in Therapeutic and Prophylactic Cancer Immunotherapy', Prof. Eli Gilboa from the Sylvester Comprehensive Cancer Center at the University of Miami will speak in our seminar on Thursday during his visit at TRON.

SITO – Seminar…
Posted 2 Monaten ago

Mainz, September 29 'Diabetes, beta-cells and reprogramming with mRNA: potential cell-based therapy for diabetes' Tomáš Koblas of the Institute for Clinical and Experimental Medicine, Prague, will talk at Seminars in Translational Oncology (SITO) during his visit at TRON.

Author summary at AS…
Posted 3 Monaten ago

Milwaukee, WI, July 23, 2016 'A message for immunity: Systemic nanoparticle RNA vaccines mimic infection to fight cancer', The American Society of Gene & Cell Therapy (ASGCT) publishes an author summary of our publication by Lena M. Kranz and colleagues in the renowned scientific journal Nature.