TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz is a biopharmaceutical research organization that pursues new diagnostics and drugs for the treatment of cancer and other severe diseases with high medical need. A focus of TRON is the development of novel platforms for individualized therapies and biomarkers, translating basic research into drug applications. TRON partners with academic institutions, biotech companies and the pharmaceutical industry, executing research with leading-edge technologies and supporting the development of innovative drugs to promote human health.

Spotlight

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Science is internati…
Science is international
Posted 7 days ago

Mainz, February 2017 – TRON supports the statement of the German Rectors´ conference emphasizing that scientific progress depends on personal exchange between academic disciplines, nations and cultures.

Find more information in the official press release of the German Rectors' conference.

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TRON Nature Publicat…
TRON Nature Publication in Top100
Posted 2 months ago

Mainz, December 13 – In June 2016 TRON published a Nature article which describes the establishment of RNA-Lipoplexes as universally applicable novel vaccine class for iv DC targeting for cancer immunotherapy. Our Nature publication has made it into the 2016 Altmetric Top 100 publication from all fields and journals - we are in 69th place. If filtering for Biological Sciences, we rank 10th and if looking through the publication in Biological Sciences in Germany you will find us…

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TRON Teams wins Silv…
TRON Teams wins Silver medal at the annual charity event “Rudern gegen Krebs (rowing against cancer)”!
Posted 6 months ago

Mainz, September 01 - Once again this year August 28th the annual charity event "Rudern gegen Krebs (Rowing Against Cancer)" took place at the Rhine riverside. The event was well-attended with 85 registered teams, despite being postponed from June to August due to Rhine’s high tide.

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TRON/BioNTech Nature…
TRON article featured in renowned Nature Journal
Posted 9 months ago

Mainz, June 01, 2016
An interdisciplinary collaboration led by TRON Managing Director Prof. Dr. Ugur Sahin establishes RNA-Lipoplexes as universally applicable novel vaccine class for iv DC targeting utilizing both adaptive as well as innate immune mechanisms for cancer immunotherapy:
“Systemic RNA delivery to dendritic cells exploits antiviral defense for cancer immunotherapy”.

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TRON at CIMT2016
TRON at CIMT2016
Posted 10 months ago

Mainz, 10 - 12 May 2016 – TRON at CIMT 2016
“Mechanisms of Efficacy in Cancer Immunotherapy”
Looking forward to the 2016 Annual Meeting of Cancer Immunotherapy in Mainz. Connect with us at booth A021 or at any of our posters.

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Review by TRON/BioNT…
TRON Review in Clinical Cancer Research
Posted 10 months ago

Mainz, April 2016 – Review in CCR Focus "Opportunities and Challenges in Cancer Immunotherapy":
“Targeting the Heterogeneity of Cancer with Individualized Neoepitope Vaccines”
TRON and BioNTech scientists have written an overview of the clinical development of individualized neoepitope cancer vaccines, which is published now as CCR Focus Review article in Clinical Cancer Research.

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Prof. Peer from the …
TRON / BioNTech in Nature Medicine News
Posted 1 year ago

Mainz, February 2016
TRON/BioNTech in Nature Medicine News Feature:
“Mutations as munitions: Neoantigen vaccines get a closer look as cancer treatment”
TRONs efforts to develop individualized cancer vaccines based on tumor-specific mutations is covered in a recent News Feature published in Nature Medicine.
For more information please click the Link below, which will direct you to the Nature Medicine website featuring the article.

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Prof. Peer from the …
Prof. Peer from the Tel Aviv University (TAU), Israel, visiting TRON
Posted 1 year ago

Mainz, October 2015 – TRON Seminar in Translational Oncology
“RNA Therapeutics : New Era in Personalized Medicine?” 
Prof. Dan Peer, PhD - Department of Cell Research and Immunology, Tel Aviv University (TAU), Israel
5 PM, Lecture Hall Building 708, University Medical Center Mainz
Langenbeckstr. 1, 55131 Mainz, Germany

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Prof. Schoenberger f…
Prof. Schoenberger from the La Jolla Institute for Allergy and Immunology visiting TRON
Posted 2 years ago

Mainz, July 2015 – TRON has the honor to host visiting Prof. Stephen Schoenberger at its facilities to promote international scientific interactions and facilitate collaborations in the fields of Immunology and Immunotherapy. Prof Schoenberger is co-author on a recent publication in Nature by TRON scientists focusing on mutated epitopes in cancer.  During his time at TRON Prof. Schoenberger will interact with different scientific teams and delve deeper into the various scientific challenges of individualized cancer vaccine research.

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Besuch einer Delegat…
Visit of a delegation from the Sultanate of Oman to TRON
Posted 2 years ago

Mainz, June 2015 – On June 1st and with generous support of the Ministry of Economics of Rhineland Palatinate, TRON welcomed a high-ranking delegation from the Sultanate of Oman for discussions on tasks and results of previous scientific works at TRON. Prof. Dr. Ulrich Förstermann of the Mainz University Medical Center also took part in the discussions.

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News

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International Childh…
Posted 1 week ago

February 15 - Each year more than 250,000 children develop cancer. In Germany, around 1,800 children 14 years and younger are diagnosed with cancer every year. The International Childhood Cancer Day on February 15th is dedicated to the many young patients taking up the battle against cancer.

Find more information about the International Childhood Cancer Day at…

Special-issue-Fronti…
Posted 2 months ago

Mainz, December 20  – TRON scientists kick off special issue in Frontiers in Immunology. This is a call for papers to provide an up-to-date overview of current efforts to understand the immunological mechanisms of neoantigen directed T-cell immunity and the attempts to harvest this source of antigens for cancer immunotherapy. Read more about the Research Topic “Neoantigens in…

11 Fakten über Krebs
Posted 3 months ago

Mainz, 23. November 2016 – Wie entstehen Krebszellen? Ist Krebs erblich? Warum ist es so schwer, Krebs zu behandeln/zu heilen und welche neuen Ansätze zur Krebsbehandlung gibt es? Welche Rolle spielt dabei die individualisierte Immuntherapie – und was ist das überhaupt? TRON und BioNTech tragen 11 Fakten über Krebs zu "Wissen im Herzen" bei, eine Video-Serie der…

SITO – Seminars in T…
Posted 3 months ago

Mainz, November 17 'The immune biology of microsatellite instability cancer: Towards a vaccine against HNPCC', Prof. von Knebel Doeberitz from the Institute of Pathology at the University of Heidelberg will speak in our seminar on Thursday during his visit at TRON.

SITO – Seminar…
Posted 4 months ago

Mainz, November 10 'Inducing Neoantigens in Therapeutic and Prophylactic Cancer Immunotherapy', Prof. Eli Gilboa from the Sylvester Comprehensive Cancer Center at the University of Miami will speak in our seminar on Thursday during his visit at TRON.