TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz is a biopharmaceutical research organization that pursues new diagnostics and drugs for the treatment of cancer and other severe diseases with high medical need. A focus of TRON is the development of novel platforms for individualized therapies and biomarkers, translating basic research into drug applications. TRON partners with academic institutions, biotech companies and the pharmaceutical industry, executing research with leading-edge technologies and supporting the development of innovative drugs to promote human health.

Spotlight

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TRON Teams wins Silv…
TRON Teams wins Silver medal at the annual charity event “Rudern gegen Krebs (rowing against cancer)”!
Posted 4 weeks ago

Mainz, September 01 - Once again this year August 28th the annual charity event "Rudern gegen Krebs (Rowing Against Cancer)" took place at the Rhine riverside. The event was well-attended with 85 registered teams, despite being postponed from June to August due to Rhine’s high tide.

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TRON/BioNTech Nature…
TRON article featured in renowned Nature Journal
Posted 4 months ago

Mainz, June 01, 2016
An interdisciplinary collaboration led by TRON Managing Director Prof. Dr. Ugur Sahin establishes RNA-Lipoplexes as universally applicable novel vaccine class for iv DC targeting utilizing both adaptive as well as innate immune mechanisms for cancer immunotherapy:
“Systemic RNA delivery to dendritic cells exploits antiviral defense for cancer immunotherapy”.

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TRON at CIMT2016
TRON at CIMT2016
Posted 5 months ago

Mainz, 10 - 12 May 2016 – TRON at CIMT 2016
“Mechanisms of Efficacy in Cancer Immunotherapy”
Looking forward to the 2016 Annual Meeting of Cancer Immunotherapy in Mainz. Connect with us at booth A021 or at any of our posters.

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Review by TRON/BioNT…
TRON Review in Clinical Cancer Research
Posted 5 months ago

Mainz, April 2016 – Review in CCR Focus "Opportunities and Challenges in Cancer Immunotherapy":
“Targeting the Heterogeneity of Cancer with Individualized Neoepitope Vaccines”
TRON and BioNTech scientists have written an overview of the clinical development of individualized neoepitope cancer vaccines, which is published now as CCR Focus Review article in Clinical Cancer Research.

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Prof. Peer from the …
TRON / BioNTech in Nature Medicine News
Posted 8 months ago

Mainz, February 2016
TRON/BioNTech in Nature Medicine News Feature:
“Mutations as munitions: Neoantigen vaccines get a closer look as cancer treatment”
TRONs efforts to develop individualized cancer vaccines based on tumor-specific mutations is covered in a recent News Feature published in Nature Medicine.
For more information please click the Link below, which will direct you to the Nature Medicine website featuring the article.

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Prof. Peer from the …
Prof. Peer from the Tel Aviv University (TAU), Israel, visiting TRON
Posted 12 months ago

Mainz, October 2015 – TRON Seminar in Translational Oncology
“RNA Therapeutics : New Era in Personalized Medicine?” 
Prof. Dan Peer, PhD - Department of Cell Research and Immunology, Tel Aviv University (TAU), Israel
5 PM, Lecture Hall Building 708, University Medical Center Mainz
Langenbeckstr. 1, 55131 Mainz, Germany

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Prof. Schoenberger f…
Prof. Schoenberger from the La Jolla Institute for Allergy and Immunology visiting TRON
Posted 1 year ago

Mainz, July 2015 – TRON has the honor to host visiting Prof. Stephen Schoenberger at its facilities to promote international scientific interactions and facilitate collaborations in the fields of Immunology and Immunotherapy. Prof Schoenberger is co-author on a recent publication in Nature by TRON scientists focusing on mutated epitopes in cancer.  During his time at TRON Prof. Schoenberger will interact with different scientific teams and delve deeper into the various scientific challenges of individualized cancer vaccine research.

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Besuch einer Delegat…
Visit of a delegation from the Sultanate of Oman to TRON
Posted 1 year ago

Mainz, June 2015 – On June 1st and with generous support of the Ministry of Economics of Rhineland Palatinate, TRON welcomed a high-ranking delegation from the Sultanate of Oman for discussions on tasks and results of previous scientific works at TRON. Prof. Dr. Ulrich Förstermann of the Mainz University Medical Center also took part in the discussions.

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TRON is part of the …
TRON is part of the Cancer Research Consortium “Immuno-Transporter” to collaborate to develop innovative appro…
Posted 1 year ago

Mainz, June, 2015 – The consortium partners will jointly develop methods to achieve tumor-specific activation of a patient's immune system to make it recognize, target and fight cancer
The newly established "IMMUNO-TRANSPORTER" consortium will collaborate to develop innovative approaches in the field of cancer immunotherapy. 

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TRON is part of the …
TRON is part of the European Bioinformatics Research Consortium on personalised cancer immunotherapy
Posted 1 year ago

Mainz, May 1, 2015 – Experts in bioinformatics and cancer immunology to develop an Advanced bioinformatics platform for personalised cancer immunotherapyOn May 1st, TRON under the leadership of Prof. Dr. med. Ugur Sahin started an innovative research project on personalised cancer immunotherapy.

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News

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SITO – Seminar…
Posted 2 days ago

Mainz, September 29 'Diabetes, beta-cells and reprogramming with mRNA: potential cell-based therapy for diabetes' Tomáš Koblas of the Institute for Clinical and Experimental Medicine, Prague, will talk at Seminars in Translational Oncology (SITO) during his visit at TRON.

Author summary at AS…
Posted 1 week ago

Milwaukee, WI, July 23, 2016 'A message for immunity: Systemic nanoparticle RNA vaccines mimic infection to fight cancer', The American Society of Gene & Cell Therapy (ASGCT) publishes an author summary of our publication by Lena M. Kranz and colleagues in the renowned scientific journal Nature.

Lena M. Kranz speaks…
Posted 2 weeks ago

Winchester, UK, September 13th "Systemic nanoparticle RNA vaccines mimic infection to fight cancer", Lena M. Kranz will speak at the 16th International Conference on Progress in Vaccination Against Cancer (PIVAC-16), Session 5.

Ugur Sahin speaks at…
Posted 4 weeks ago

Verona, September 7th TRON Managing Director Prof. Ugur Sahin will speak at the Annual Meeting of the Italian Cancer Society 2016. Ugur Sahin will talk about "RNA based cancer immunotherapy" in the session Cancer immunotherapy (5:00 pm, 2016-09-07).

Ugur Sahin speaks at…
Posted 1 month ago

Vienna, September 01 2016 TRON Scientific Manager Ugur Sahin will speak at the World Congress on Cancers of the Skin 2016. His talks will cover "Mutanome specific personalized vaccination" (11:30 a.m., 2016-09-01) and "RNA based mutanome specific vaccines – a true personalized therapy" (6:00 p.m., 2016-09-01).