TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz is a biopharmaceutical research organization that pursues new diagnostics and drugs for the treatment of cancer and other severe diseases with high medical need. A focus of TRON is the development of novel platforms for individualized therapies and biomarkers, translating basic research into drug applications. TRON partners with academic institutions, biotech companies and the pharmaceutical industry, executing research with leading-edge technologies and supporting the development of innovative drugs to promote human health.

Spotlight

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Review by TRON/BioNT…
TRON Review in Clinical Cancer Research
Posted 2 weeks ago

Mainz, April 2016 – Review in CCR Focus "Opportunities and Challenges in Cancer Immunotherapy":
“Targeting the Heterogeneity of Cancer with Individualized Neoepitope Vaccines”
TRON and BioNTech scientists have written an overview of the clinical development of individualized neoepitope cancer vaccines, which is published now as CCR Focus Review article in Clinical Cancer Research.

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Prof. Peer from the …
TRON / BioNTech in Nature Medicine News
Posted 3 months ago

Mainz, February 2016
TRON/BioNTech in Nature Medicine News Feature:
“Mutations as munitions: Neoantigen vaccines get a closer look as cancer treatment”
TRONs efforts to develop individualized cancer vaccines based on tumor-specific mutations is covered in a recent News Feature published in Nature Medicine.
For more information please click the Link below, which will direct you to the Nature Medicine website featuring the article.

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Prof. Peer from the …
Prof. Peer from the Tel Aviv University (TAU), Israel, visiting TRON
Posted 7 months ago

Mainz, October 2015 – TRON Seminar in Translational Oncology
“RNA Therapeutics : New Era in Personalized Medicine?” 
Prof. Dan Peer, PhD - Department of Cell Research and Immunology, Tel Aviv University (TAU), Israel
5 PM, Lecture Hall Building 708, University Medical Center Mainz
Langenbeckstr. 1, 55131 Mainz, Germany

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Prof. Schoenberger f…
Prof. Schoenberger from the La Jolla Institute for Allergy and Immunology visiting TRON
Posted 10 months ago

Mainz, July 2015 – TRON has the honor to host visiting Prof. Stephen Schoenberger at its facilities to promote international scientific interactions and facilitate collaborations in the fields of Immunology and Immunotherapy. Prof Schoenberger is co-author on a recent publication in Nature by TRON scientists focusing on mutated epitopes in cancer.  During his time at TRON Prof. Schoenberger will interact with different scientific teams and delve deeper into the various scientific challenges of individualized cancer vaccine research.

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Besuch einer Delegat…
Visit of a delegation from the Sultanate of Oman to TRON
Posted 11 months ago

Mainz, June 2015 – On June 1st and with generous support of the Ministry of Economics of Rhineland Palatinate, TRON welcomed a high-ranking delegation from the Sultanate of Oman for discussions on tasks and results of previous scientific works at TRON. Prof. Dr. Ulrich Förstermann of the Mainz University Medical Center also took part in the discussions.

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TRON is part of the …
TRON is part of the Cancer Research Consortium “Immuno-Transporter” to collaborate to develop innovative appro…
Posted 11 months ago

Mainz, June, 2015 – The consortium partners will jointly develop methods to achieve tumor-specific activation of a patient's immune system to make it recognize, target and fight cancer
The newly established "IMMUNO-TRANSPORTER" consortium will collaborate to develop innovative approaches in the field of cancer immunotherapy. 

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TRON is part of the …
TRON is part of the European Bioinformatics Research Consortium on personalised cancer immunotherapy
Posted 11 months ago

Mainz, May 1, 2015 – Experts in bioinformatics and cancer immunology to develop an Advanced bioinformatics platform for personalised cancer immunotherapyOn May 1st, TRON under the leadership of Prof. Dr. med. Ugur Sahin started an innovative research project on personalised cancer immunotherapy.

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Auf dem Weg zu einer…
Auf dem Weg zu einer individualisierten Immuntherapie bei Krebs
Posted 1 year ago

Mainz, April 23, 2015 – Auf dem Weg zu einer individualisierten Immuntherapie bei Krebs
Neue immunologische Erkenntnisse und technologische Fortschritte ebnen den Weg für maßgeschneiderte Krebsimpfstoffe / klinische Studie läuft bereits

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Medizin des 21. Jahr…
Call for Papers: RNA Vaccination Therapy
Posted 1 year ago

Mainz, February 28, 2015 – TRON IDC Heads to lead Special Edition in Journal of Immunology Research
In the field of therapeutic cancer vaccination in vitro transcribed synthetic mRNA (IVT RNA) has gained high interest in the recent years as a drug format not only for cancer immunotherapy, but also for the development of antiviral mRNA based vaccines and innovative concepts adopted from viruses to achieve self-replication.

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Medizin des 21. Jahr…
Medizin des 21. Jahrhunderts
Posted 1 year ago

Mainz, November 26, 2014 – "In the lecture series "University in the City Hall," scientists of the Mainz University Medical Center will present a range of current research topics to the general public. In addition to looking at how research is transformed into clinical application, they will also be outlining concepts for innovative future treatments."

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News

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TRON Seminar in Tran…
Posted 2 weeks ago

Mainz, April 28 2016 “Exploiting Natural Killer cells for immunotherapy of cancer”, PD Dr. rer. nat. Adelheid Cerwenka from the German Cancer Research Center (DKFZ) is visiting TRON.

Prof. Hämmerling fro…
Posted 1 month ago

Mainz, April 7 2016 “Regulation of tumor immunity by macrophage and eosinophils”, Prof. Günter Hämmerling from the German Cancer Research Center (DKFZ) is visiting TRON.

Vortrag auf dem Worl…
Posted 2 months ago

Davos, March 16, 2016 - "Eliciting potent T-cells against individual mutant neoantigens – the mutanome as rich target source for individualized cancer vaccination" TRON scientist  Dr. Sebastian Kreiter will speak at the 10th World Immune Regulation Meeting in Davos (Switzerland) in the Session "Immune Tolerance".

Vortrag 32. Deutsche…
Posted 2 months ago

Berlin, February 25, 2016 - "New Methods for the identification of Tumor Antigens as Targets for Tumor vaccines" Mathias Vormehr will speak at the German Cancer Congress in Berlin in the session "Translational Oncology".

Univ.-Prof. Dr. Dr. …
Posted 7 months ago

Mainz, October 19, 2015Honor
Univ.-Prof. Dr. Dr. h.c. Christoph Huber receives Federal Cross of Merit 1st class