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TRON-Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz is biopharmaceutical research organization that pursues new diagnostics and drugs for the treatment of cancer and other severe diseases with high medical need. A focus of TRON is the development of novel platforms for individualized therapies and biomarkers, translating basic research into drug applications. TRON partners with academic institutions, biotech companies and the pharmaceutical industry, executing research with leading-edge technologies and supporting the development of innovative drugs to promote human health.

Spotlight

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Prof. Schoenberger f…
Prof. Schoenberger from the La Jolla Institute for Allergy and Immunology visiting TRON
Posted 7 days ago

Mainz, July 2015 – TRON has the honor to host visiting Prof. Stephen Schoenberger at its facilities to promote international scientific interactions and facilitate collaborations in the fields of Immunology and Immunotherapy. Prof Schoenberger is co-author on a recent publication in Nature by TRON scientists focusing on mutated epitopes in cancer.  During his time at TRON Prof. Schoenberger will interact with different scientific teams and delve deeper into the various scientific challenges of individualized cancer vaccine research.

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Besuch einer Delegat…
Visit of a delegation from the Sultanate of Oman to TRON
Posted 1 month ago

Mainz, June 2015 – On June 1st and with generous support of the Ministry of Economics of Rhineland Palatinate, TRON welcomed a high-ranking delegation from the Sultanate of Oman for discussions on tasks and results of previous scientific works at TRON. Prof. Dr. Ulrich Förstermann of the Mainz University Medical Center also took part in the discussions.

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TRON is part of the …
TRON is part of the Cancer Research Consortium “Immuno-Transporter” to collaborate to develop innovative appro…
Posted 1 month ago

Mainz, June, 2015 – The consortium partners will jointly develop methods to achieve tumor-specific activation of a patient's immune system to make it recognize, target and fight cancer
The newly established "IMMUNO-TRANSPORTER" consortium will collaborate to develop innovative approaches in the field of cancer immunotherapy. 

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TRON is part of the …
TRON is part of the European Bioinformatics Research Consortium on personalised cancer immunotherapy
Posted 2 months ago

Mainz, May 1, 2015 – Experts in bioinformatics and cancer immunology to develop an Advanced bioinformatics platform for personalised cancer immunotherapyOn May 1st, TRON under the leadership of Prof. Dr. med. Ugur Sahin started an innovative research project on personalised cancer immunotherapy.

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Auf dem Weg zu einer…
Auf dem Weg zu einer individualisierten Immuntherapie bei Krebs
Posted 3 months ago

Mainz, April 23, 2015 – Auf dem Weg zu einer individualisierten Immuntherapie bei Krebs
Neue immunologische Erkenntnisse und technologische Fortschritte ebnen den Weg für maßgeschneiderte Krebsimpfstoffe / klinische Studie läuft bereits

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Medizin des 21. Jahr…
Call for Papers: RNA Vaccination Therapy
Posted 5 months ago

Mainz, February 28, 2015 – TRON IDC Heads to lead Special Edition in Journal of Immunology Research

In the field of therapeutic cancer vaccination in vitro transcribed synthetic mRNA (IVT RNA) has gained high interest in the recent years as a drug format not only for cancer immunotherapy, but also for the development of antiviral mRNA based vaccines and innovative concepts adopted from viruses to achieve self-replication.

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Medizin des 21. Jahr…
Medizin des 21. Jahrhunderts
Posted 8 months ago

Mainz, November 26, 2014 – "In the lecture series "University in the City Hall," scientists of the Mainz University Medical Center will present a range of current research topics to the general public. In addition to looking at how research is transformed into clinical application, they will also be outlining concepts for innovative future treatments."

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Genomics-guided RNA-…
Genomics-guided RNA-based personalized cancer vaccines
Posted 9 months ago

Mainz, October 16, 2014 – Cancer is a disease caused by DNA mutations. 95% of the mutations in a tumor are unique to that single patient and only a small number of mutations are shared between patients. Therefore, a mutation-targeting individualized therapy would benefit each single patient. In the recent edition of the British Journal of Cancer, TRON researchers explain how next-generation sequencing may enable the rapid identification of somatic mutations in individual tumors, paving the way for clinical…

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TRON guest lecture O…
TRON guest lecture October 2:  Fighting the Ebola Beast: the Race between a Big Virus and Little Antibodies
Posted 10 months ago

Mainz, September 30, 2014 – On October 2, Dr. Javad Aman, will give a guest lecture on the clinical development of a vaccine for Ebola. The 1 p.m. lecture at Building 708, at University Medical Center Mainz takes place as part of the TRON Seminar Series in Translational Oncology.

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Mining the genetic i…
Mining the genetic information of cancer cell lines for future therapy development
Posted 10 months ago

Mainz, September 15, 2014 – Cancer cell lines are a tremendous resource for cancer biology and therapy development. In a new research paper in the September issue of OncoImmunology, TRON scientists determined the HLA type and HLA expression of 167 cancer and 10 non-cancer cell lines frequently used for the identification of novel tumor targets and the development of cancer immunotherapies.

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News

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TRON in the news
Posted 3 months ago

Focus Online – Revolution in der Krebsforschung

ARD – Krebs: Fortschritte bei Immuntherapie

SAT 1 – Neuer Erfolg im Kampf gegen Krebs

Kaufmännischer Gesch…
Posted 6 months ago

Mainz, Germany, January 20, 2015 -Die Akteure, Unternehmen und Netzwerke der Gesundheitswirtschaft in Rheinland-Pfalz haben einen zentralen Verein gegründet: InnoNet Health Economy e.V.. Ziel des Vereins ist es, den Informations- und Erfahrungsaustausch der Branche zu stärken, neue Kooperationspartner zu identifizieren und weitere Systemlösungen zu entwickeln.

TRON Seminar in Tran…
Posted 8 months ago

Mainz, December 3, 2014 - "New preclinical test system for an improved analysis of monoclonal antibody function" with Prof. Dr. Ulrich Kalinke – TWINCORE, Hannover, Germany

Translational Medici…
Posted 9 months ago

Mainz, Germany, October 31, 2014
Translational Medicine: Transforming research achievements into innovative therapeutic and diagnostic products
The translation of biomedical research into effective therapeutics and diagnostics is the driving factor for innovation in the pharmaceutical industry.

TRON Seminar in Tran…
Posted 9 months ago

Mainz, October 23, 2014 - "Image-Guided Drug Delivery" with Dr. Twan Lammers – Helmholtz Center for Biomedical Engineering, Aachen