TRON @ Twitter:

Don't miss Fulvia Vascotto's talk today at #ImmunoRad21 : "The GOOD, the ELDER & the BAD: #RNAVaccine & Radiotherapy to fight #Cancer" . International conference in #Paris on #immunotherapy and #radiotherapy combinations.

To analyze #SARSCoV2 genomes and to track mutations, we have built the #CoVigator analysis pipeline, knowledge base and web portal. The analysis runs on @Intel Server computing nodes. #Intel was so kind to highlight our story!

We are proud to have contributed to a recently published preclinical study led by @BioNTech_Group and @SanofiUS on intratumoral administration of #mRNA encoding cytokines promoting antitumor immunity and #tumor eradication! #cancer #immunotherapy

For the further development of our pipeline for personalized #cancer vaccines, we are hiring a #Bioinformatics #SoftwareDeveloper (m/f/d) with a strong background in software engineering and computation!

Unsere Kollegen Tim Beißert und David Weber erklären am Mittwoch (1.9., 18:00 h) im Meenzer Science-Schoppe Potential und Funktion therapeutischer #mRNA (virtueller Vortrag).
#Mainz #WissenImHerzen @mainz_de

Our team Personalized Cancer #Genomics has an open position for a #Bioinformatics/Data Scientist (m/f/d) to support the development of our personalized #cancer vaccine platform.





Press Releases

  • Official foundation ceremony of HI-TRON Mainz (Feburary, 2019)
  • Cooperation agreements signed between TRON and DKFZ to found HI-TRON Mainz (August, 2018)
  • Prof. Ugur Sahin receives prestigious European Research Council (ERC) Advanced Grant for personalized cancer vaccines (April, 2018)
  • TRON receives three-year research grant from the Falconwood Foundation to develop new treatment approaches for neuroendocrine tumors (February, 2018)
  • TRON collaborates with its industrial partner BioNTech in a first-ever clinical study demonstrating that personalized RNA-based vaccines using mutant neo-epitopes as antigens activate immune system against individual mutations and exert anti-cancer activity. (July, 2017)
  • TRON as a partner in a collaboration with industrial and academic experts in the field of immunology and cancer research, to develop, improve and optimize immunomodulatory concepts for increased efficacy and improved tolerability of cancer immunotherapies. (June, 2015)  
  • TRON is a partner in the newly established multi-partnered Horizon 2020 funded consortium APERIM, which will collaborate on the practical implementation of immunotherapy and the development of a new treatment platform specifically for unique tumour mutations of individual patients. (May 1, 2015) 
  • Auf dem Weg zu einer individualisierten Immuntherapie bei Krebs
    Neue immunologische Erkenntnisse und technologische Fortschritte ebnen den Weg für maßgeschneiderte Krebsimpfstoffe / klinische Studie läuft bereits (March 23, 2015). 
  • TRON and TheraCode together with Merck begin collaboration on identification and development of biomarkers for antigen-specific cancer immunotherapy (October 18, 2012).
  • First preclinical proof-of-concept of mutation-based individualized cancer vaccine. Deep sequencing of immunogenic mutations may pave way for customized immunotherapy (Jan 17, 2012). 
  • New Variant Analysis Software from Ingenuity Used to Identify DNA Variants for Personalized Medicine Research (Jan 9, 2012). 
  • Der Brückenschlag: Translationale Medizin.
    (© Das PDF zum Wissenschaftsmagazin dient lediglich der privaten Verwendung, es darf nicht kommerziell vervielfältigt und verbreitet werden. Alle Rechte liegen bei der Tempus Corporate GmbH)
  • New Convey Graph Constructor Leverages Hybrid-Core Architecture to Speed De Novo Genome Assembly (May 17, 2011). 
  • Next-generation sequencing technology for medicine and research in Mainz. Center for Translational Oncology and Immunology (TRON) Mainz has received one of the world’s first Illumina HiSeq genome sequencers (June 6, 2010).