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TRON scientists publish in Molecular Therapy

Mainz, September 27, 2019 – TRON scientists publish in Molecular Therapy TRON has published an article on a novel RNA-based vector for antigen delivery in Molecular Therapy. Among the exciting results, the authors show that trans-amplifying RNA as a vaccine vector induces protective immune responses against influenza challenge in mice, at a 400x lower dose

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TRON scientists publish in Oncoimmunology

Mainz, July 19, 2019 – TRON scientists publish in Oncoimmunology TRON has published an article on the immunomodulatory effects of the TLR7 agonist SC1 in Oncoimmunology.  Among the exciting results, the authors show that SC1 administration leads to inhibition of tumor growth and prolonged survival, and that this effect is dependent on CD8+ T cells. 

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TRON scientists are co-authors in a Nature Communications article

Mainz, December 6, 2018 – TRON scientists are co-authors in a Nature Communications article In collaboration with scientists from Italy and Germany, TRON has co-authored an article on the induction of immunosuppressive functions in monocytes by c-FLIP, published in Nature Communications.  The data show that modulation of c-FLIP in monocytes may offer a path to

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Ugur Sahin co-authors Nature Reviews Drug Discovery article

Mainz, September 11, 2018 – TRON is thrilled to announce a review co-authored by Ugur Sahin in the journal Nature Reviews Drug Discovery.   This article gives an over view of nascent RNA immunotherapeutics, including RNA vaccines encoding cancer neoantigens, mRNAs encoding immunomodulatory factors, viral RNA analogues, interference RNAs and protein-binding RNA aptamers. These approaches

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Sebastian Kreiter speaks at the Goethe University Translational Immunology seminar

Mainz, November 24, 2017 – The University Clinic of Goethe University in Frankfurt is hosting a seminar as part of the German Society for Immunology’s Translational Immunology series.  In this context, Sebastian Kreiter will be speaking on “Neo-antigen vaccination in cancer – translating science into survival.” Dr. Kreiter’s presentation will take place on Thursday, 30.

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TRON at the EMBL Conference – Cancer Genomics

Mainz, October 27, 2017 – EMBL’s Cancer Genomics Conference offers a fabulous opportunity to keep up to date with the rapidly progressing area of cancer genomics. Presentations cover the latest from cancer genome projects, cancer functional genomics, systems biology, cancer immunogenomics and epigenomics, cancer mouse models and the translation and clinical impact of scientific results.  

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Neue Krebsimmuntherapien – Ugur Sahin im Expertengespräch

Was versprechen neuartige personalisierte Krebsimmuntherapien? Wie können Patienten von Ihnen profitieren, und welche Risiken bergen die Behandlungen? Zwei neue Ansätze in der Krebsimmuntherapie sind die CAR-T-Methode und die so genannten Neoantigen-Vakzine. Beide werden gerade getestet und sind sehr vielversprechend. Der regionale Radiosender SWR2 sendete hierzu einen Radiobeitrag in seinem Programm. Einen Mitschnitt sowie ein Transkript

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