TRON Seminar in Translational Oncology: Dr. J. Korbel

April 18, 2013

2:30-3:30 PM in Mainz, Germany

TRON – Building 708 at University Medical Center Mainz

Langenbeckstr. 1

55131 Mainz

Dr. Jan Korbel

Group Leader – Genome Biology (EMBL) Heidelberg, Germany

“Origin, complexity and impact of DNA structural rearrangements in cancer”

He is Group Leader at the European Molecular Biology Laboratory (EMBL) in Heidelberg and working on the origin and function of genomic variation . His group takes part in the 1000 Genomes Project and participates in the International Cancer Genome Consortium.

In this context Jan Korbel’s group identified catastrophic DNA rearrangements called chromothripsis in the development of cancer (Cell. 2012 Jan 20;148(1-2):59-71). Another major recent contribution of his group was the mapping of copy number variation by population-scale genome sequencing (Nature. 2011 Feb 3;470(7332):59-65).

For further information, please take a look at the following links: