TRON Seminar in Translational Oncology: Dr. Tiwari

June 14, 2012

5 PM in Mainz, Germany
TRON – Building 708 at University Medical Center Mainz

Langenbeckstr. 1

55131 Mainz

Dr. Vijay Tiwari

Institute for Molecular Biology, Mainz,  Germany

“Epigenetic Regulation of Cellular Differentiation”

Dr. Tiwaris lab focuses on understanding how cell signaling events crosstalk to chromatin to mediate transcriptional regulation during development and differentiation. The research is aimed at achieving an integrated molecular and systems-level understanding of the mechanisms by which intracellular signal transduction cascades execute a diverse repertoire of transcriptional responses and how this communicates with epigenetic modifiers at gene promoters. Tiwaris team employs high throughput epigenomics assays such as ChIP-seq and RNA-seq in combination with stem cell biology and cutting-edge epigenetics and molecular biology tools. The resulting dataset will be analyzed using computational biology approaches to generate a comprehensive model of signaling to chromatin crosstalk during development and differentiation.

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