Aims and Expertise

TRON is a non-profit spin-off from the University Medicine Mainz and to this day its labs and offices remain close to the University campus.

Our aim is to translate scientific findings into the clinic in collaboration with industry partners. To achieve this, we are active in basic, application-driven research in the fields of oncology and immunology. Within those fields, we are especially focused on tailor-made therapies and diagnostics. By developing strategies for novel immunotherapeutic approaches or clinically relevant biomarkers, we lay the foundations for individualized therapies of patients.


TRON is structured to readily integrate ideas, modern technologies as well as know-how in genomics, DNA and RNA sequencing, bioinformatics, biostatistics, immunology, immunotherapies and molecular biology.

For all these tasks, we have a team of excellent employees from all around the world, which excel in their respective fields and want to help push ourselves further.


TRON’s competencies are organized into two central research departments as well as the administrative department. The Biomarker Development Center (BDC) discovers and validates clinically relevant molecular, cellular or serological biomarkers. The Immunotherapy Development Center (IDC) on the other hand is involved in the development of novel immunotherapeutic strategies. This includes monoclonal antibodies, recombinant vaccines as well as adoptive cell transfers and gene therapies. Both departments use state of the art technologies and laboratories for quality-controlled research.

Our aims:

  • Research at the forefront of technology in the areas of oncology, immunology with focus on cancer genomics, cancer immune recognition and immunotherapy.
  • Active tech transfer of innovations. Both the improvement and validation of research results and the evaluation of the potential of commercialization of an idea or patent are of great significance. Many of our patents are already licensed to industry partners and are being used in clinical trials.
  • Collaborations with the biotech and pharma industry in research projects up to the pre-clinical proof of concept or beyond. This aids in the successful development of commercially available products.
  • Training of young scientists in the areas of cancer research, immunology and all aspects of translational research.

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