The concept of delivering genetic material to defective cells to treat diseases or to vaccinate healthy people against infections has been around for quite some time. Nevertheless, key challenges remain, such as efficient delivery of the material as well as duration of gene expression.
In the course of evolution, the immune system has developed sophisticated mechanisms to identify and eliminate invading pathogens and degenerate cells, thereby preventing infection and tumor occurrence. When these mechanisms are ineffective or somehow bypassed, tumors or chronic infections may form. Clarifying the processes leading to ineffective immune defense is the central goal of the
The Antibody Engineering and Therapeutics conference will take place December 11th-15th 2017 at the Manchester Grand Hyatt in San Diego, California.
The Berlin Institute of Health, together with the Charité Universitätsmedizin Berlin, Max Delbrück Center for Molecule Medicine and Tagesspiegel, will host the second Future Medicine: Innovation in Health Science meeting on 7th November.
Mainz, 2017-10-25 – TRON scientific advisor Prof. Dr. Dr. Cornelis J. Melief, Leiden, Netherlands, will be awarded with the degree of an honorary medical doctor. Melief will be awarded for his lifetime achievements as a pioneer of tumor immunology, as well as for his commitment and deserts regarding immunological research in Mainz. Further information about
The topic of this year’s EFIS-EJI Ruggero-Ceppellini Advanced School of Immunology is “Tumour Immunology: from tissue microenvironment to immunotherapy.”
The National Cancer Institute’s Center of Excellence in Immunogy sponsors a two-day symposium with the theme “Cancer Immunology and Immunotherapy: From Conception to Delivery”.
The Institute for Molecular Life Sciences at Radboud University Medical Center (RIMLS) will host a mini-symposium entitled “Chemical Immunology”.
The 1st Crick International Cancer Conference will bring together leading cancer scientists from all over the world to discuss the latest findings in cancer metabolism, the tumor microenvironment, and how the cancer genotype changes over time.
Mainz, September 23, 2017 – The Annual Meeting of the Leopoldina National Academy of Sciences will be held on 22 and 23 September in Halle (Saale).
Mainz, September 21, 2017 – The working group Dermatological Oncology (ADO) organizes from 21-23 September the 27th German Skin Cancer Congress in the Rheingoldhalle Mainz.
Among nucleic acid-based delivery platforms, self-amplifying RNA (saRNA) vectors are of increasing interest for applications such as transient expression of recombinant proteins and vaccination. Although saRNA is a promising technology, antigen expression from saRNA is limited by the host cells’ innate interferon response. TRON’s Tim Beissert and colleagues show, in an upcoming issue of Human