In the course of evolution, the immune system has developed sophisticated mechanisms to identify and eliminate invading pathogens and degenerate cells, thereby preventing infection and tumor occurrence. When these mechanisms are ineffective or somehow bypassed, tumors or chronic infections may form. Clarifying the processes leading to ineffective immune defense is the central goal of the Collaborative Research Center (SFB) 1292, “Targeting convergent mechanisms of inefficient immunity in tumors and chronic infections”. The results from this SFB should help inform new immunotherapeutic approaches.
With effect from 1 January 2018, the DFG is launching the SFB 1292 at the University Medical Center of Johannes Gutenberg University Mainz (JGU). The SFB will be funded with around 9.7 million Euros for an initial period of four years. TRON is involved in the cooperation with the sub-project “Neo-epitope-specific CD4+ T cells – Anti-tumoral mechanisms and their modulation” as well as the service project “Integrated OMICS and Bioinformatics Platform”.
Further information is available in the official press release.
Source Logo SFB 1292: University Medical Center Mainz