TRON Publication in Cancer Immunology, Immunotherapy

Mainz, July 15 2016 “Uptake of synthetic naked RNA by DCs allows antigen expression and induction of T-cell responses in mice”, the authors shed light on the underlying mechanism of RNA uptake by dendritic cells after intradermal administration of antigen-encoding naked RNA, antigen translation and presentation and priming of antigen-specific T-cells. The study was led by TRON scientists and has been published in the peer-reviewed Journal of Cancer Immunology, Immunotherapy.