TRON Seminar in Translational Oncology

Mainz, April 7 2016 – “Regulation of tumor immunity by macrophage and eosinophils”, Prof. Günter Hämmerling from the German Cancer Research Center (DKFZ) is visiting TRON.

5 PM, Lecture Hall Building 708, University Medical Center Mainz, Langenbeckstr. 1, 55131 Mainz, Germany

Upon completion of his PhD on the structure of LPS at the Max Planck Institute for Immunobiology in Freiburg, Germany, in 1971, Günter Hämmerling joined the laboratory of Hugh McDevitt at the Stanford University Medical School, USA, for postdoctoral studies devoted to the function of MHC linked “immune response genes”, resulting in the description of Ia antigens, known today as MHC class II. In 1974 he joined the laboratory of Klaus Rajewsky at the Institute for Genetics, University of Cologne, Germany, where he introduced monoclonal antibodies for the functional analysis of MHC molecules. Since 1979 Günter Hämmerling has held the position of Chairman of the Division of Molecular Immunology at the German Cancer Research Center Heidelberg (DKFZ), Germany, where the work on MHC molecules was extended to antigen presentation components, peripheral tolerance and tumor immunology. This work led to the clinically important observation that the degree of T cell infiltration into tumors can be manipulated genetically or by inflammatory mediators, resulting in more efficient elimination of tumors.

Günter Hämmerling is a member of the European Molecular Biology Organization EMBL. He served on various Scientific Advisory Boards including the Helmholtz Center for Infection Research (HZI) in Braunschweig, the German Center for Rheumatology Research (DRFZ) in Berlin, the Association for Immunotherapy of Cancer (CIMT) in Mainz and the World Premier Institute in Japan. He was co-founder and president of the European Network of Immunology Institutes (ENII), and president of the German Society of Immunology (DGfI). He also serves on a number of editorial boards of scientific journals. To date, he has authored more than 350 publications in leading scientific journals.

Information about his publications can be found at: http://www.ncbi.nlm.nih.gov/pubmed/?term=Hammerling+GJ%5BAuthor%5D

 

Keywords: tumor immunity, cancer immunotherapy, cytotoxic T cells, eosinophils, macrophages