February 21, 2013
5 PM in Mainz, Germany
TRON – Building 708 at University Medical Center Mainz
Richard Scheuermann, PhD
J. Craig Venter Institute, Director of Informatics, San Diego, USA
“Unsupervised clustering and supervised classification for the automated analysis of flow cytometry data”
Richard H. Scheuermann, Ph.D., Director of Informatics at JCVI, has established a productive research program investigating signal transduction pathways that regulate normal lymphocyte development and function that induce cell cycle arrest and apoptosis in lymphomas, supported through numerous research grants from the National Institutes of Health, the American Cancer Society, the Texas Higher Education Coordinating Board, and other granting agencies. In the Pathology Department, he also worked on the development and validation of novel diagnostic methods for viruses that mediate chronic infectious disease and for chromosomal translocations that drive leukemia and lymphoma development. Since 2001, Dr. Scheuermann has applied his deep knowledge in molecular immunology and infectious disease toward the development of novel computational data mining methods and knowledge representation approaches, including the development of biomedical ontologies and their use in data mining, novel methods for the analysis of gene expression, protein network and flow cytometry data, and novel comparative genomics methods. These knowledge representation approaches and computational methods have been made available to the research community through several public database and analysis resources, including the Influenza Research Database (IRD; www.fludb.org), the Virus Pathogen Resource (ViPR; www.viprbrc.org) and the Immunology Database and Analysis Portal (ImmPort; www.immport.org) supported by the National Institutes of Health. At JCVI he is also expanding his bioinformatics research program into the area of human genomics.